White House Commits $5B+ to Genesis Mission, DOE Funds First 278 AI-for-Science Projects
The White House·medium signal
What began as a DOE program under a November 2025 executive order is now a whole-of-government initiative spanning 15+ federal agencies, 340+ institutions, a $293.76M grants program, and over $500M in private consortium contributions. DOE named the first 278 funded projects; the largest single award is $60M for Prometheus, a three-year effort using AI to design, license, manufacture, and operate nuclear reactors. Challenge areas span health care, energy, infrastructure, manufacturing, and affordability.