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Shopify CEO Validates Karpathy's Autoresearch: 19% Performance Gain from 37 Overnight Experiments
Shopify CEO Tobias Lütke ran Karpathy's open-source Autoresearch framework on internal data, achieving a 19% performance gain after 37 overnight experiments — outperforming Karpathy's own 11% from 20 tweaks. This is the first major enterprise validation of the 'AI agents run experiments while you sleep' paradigm, proving the framework generalizes beyond research to production optimization at a $100B+ company.
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