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Research2026-06-24 · source-backed

GPT-5 Pro cracks a 3-year-old immunology mystery, then has to survive the bench.

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OpenAI published a case study where immunologist Derya Unutmaz fed GPT-5 Pro unpublished flow-cytometry data on CD4+ T cells under glucose/2-DG conditions. The model proposed that disrupted N-linked glycosylation during priming, driven by memory rather than naive T cells, explained the anomaly. The honest framing is the valuable part: the hypothesis still had to survive bench validation, and the model worked inside a frame a human scientist built. Hypothesis-generation compression, not replacement.

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2026-06-24-gpt-5-pro-cracks-a-3-year-old-immunology-mystery-then-has-to-survive-the-bench
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source-backed, canonical briefing excerpt