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Research2026-08-20 · source-backed
Anthropic ran a de novo binder campaign where Claude researched each target's biology, picked docking sites, installed open-source tools from their public repos itself, and composed 24 workflows with no human making a design decision. Of 1,320 designs synthesized and measured by Adaptyv Bio and Twist Bioscience, 354 bound. Claude Mythos Preview hit 26.7% multi-target and 35.1% single-target against a stated 10-15% industry baseline, using up to 12,500 H100-hours. (Anthropic) Prompts, raw NMR/LC-MS files and complex models are on Hugging Face, so it doubles as a reproducible benchmark. Peer review is still pending, which is the caveat to hold. But note the contrast with the two findings above: this worked because binding affinity is a hard measurable, and the agent's judgment was checked by a wet lab rather than by itself.
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Anthropic released Claude / Shared entities / Same source domain / Shared topic / Earlier coverage
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Anthropic released Claude / Shared entities / Same source domain / Shared topic / Earlier coverage / Tension
Linked by a graph relationship (Anthropic released Claude); both cover Anthropic, Claude; reported by the same outlet (anthropic.com).
Linked by a graph relationship (Anthropic released Claude); both cover Anthropic, Claude; reported by the same outlet (anthropic.com).
Anthropic released Claude / Shared entities / Same source domain / Shared topic / Earlier coverage
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Anthropic released Claude / Shared entities / Shared topic / Earlier coverage
Linked by a graph relationship (Anthropic released Claude); both cover Anthropic, Claude, Hugging Face; overlapping topics (against, agent, anthropic).
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